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Enterprise

Astrazeneca bows to Donald Trump and slashes US drug prices by up to 80%
By City AM
The Cambridge-based pharma giant said it will provide direct-to-consumer sales to eligible patients with prescriptions for chronic diseases at a discount of up to 80 per cent off list prices
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The Savoy Hotel's losses widen as it sheds jobs and starts major renovation project
By City AM
The five-star London hotel has posted a pre-tax loss of 拢19.6m for 2024, having also lost 拢17.5m in 2023.
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William Hill owner confirms 200 shop closures as industry faces budget uncertainty
By City AM
The betting giant is eyeing up to 200 closures as its parent company Evoke looks to steady its heavily indebted balance sheet ahead of a potential tax raid in next month's budget
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Northumbria University student to pitch to TV Dragon in national awards final
Technology
Daniel Indi Te has developed a digital healthcare platform designed to help people with musculoskeletal care
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People on the move: key North East appointments and promotions
People
Companies making new appointments and promotions this week include:
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VAT hike would have 'serious negative impact' on 海角视频, economists warn Rachel Reeves
By City AM
A VAT hike would have the biggest negative impact of any major tax rise, leading to a 0.9 per cent fall in GDP in the first year after the tax is applied, according to an analysis by the National Institute of Economic and Social Research (NIESR)
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Royal IHC talks of "turning point" in North East operations following difficult years
Engineering
The marine engineering specialist has published accounts in which it talks of reaching breakeven
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Proposal calls for public-private partnership to save Lindsey Oil Refinery
Enterprise
Investor Marc Amram, who heads an investment consortium, has appealed to the Government
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Hull's Tucker Mechanical and Electrical Building Services enters administration
Enterprise
Tucker Mechanical and Electrical Building Services was first launched in 1973 as Neville Tucker Heating Ltd
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New budget headache for Chancellor Rachel Reeves as the number of job seekers spikes
By City AM
The number of job seekers has spiked while a rise in starting salaries was "fractional" - signs that the jobs market is struggling to shake off higher taxes and low growth prospects.
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Channel 4 sets streaming records in the 海角视频, secures expansive content deal with 海角视频TV
By City AM
Channel 4 has been named the 海角视频's fastest-growing major streaming platform, beating multiple audience records in September and strengthening its digital hand with a new deal designed to rival the reach of Netflix and Disney+
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Cornwall Angel Network celebrates first anniversary
South West
A number of companies in the Duchy have received investment from the network over the last 12 months
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Treasury 'lobbied to block China audit' as questions mount over collapsed espionage trial
By City AM
The Treasury lobbied the Prime Minister's national security adviser to block reports on the threat posed by China in the midst of the probe against the two men accused of spying for Beijing
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MOBOs founder Kanya King to speak at Manchester conference to inspire next generation of black women in business
Black Communities
Mother-daughter duo Sharon and Afiya Amesu set up She Leads for Legacy to help black women succeed
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10 questions for Alex Franklin of Hedley Planning Newcastle
People
The head of the planning consultancy's Newcastle office answers our questions
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York's Aptamer Group secures work with 'top three' global pharma customer
Pharmaceuticals
Its latest contract is to develop binders for use in the multibillion dollar radiopharmaceuticals market.
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Controversial quarry plans in small village recommended for refusal after strong local opposition
Enterprise
Applicants say local building industry needs a new sand and gravel quarry
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Bath youth wellbeing charity announces new chief executive
Appointments
I Can & I Am was founded in 2015 by former teacher James Shone who was left partially sighted after a brain tumour
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Grainger hails another year of rental growth with earnings on track to rise 50% within next four years
Enterprise
The build-to-rent specialist said its portfolio has not really been impacted by economic headwinds
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Hargreaves Lansdown co-founder to step down from board after 拢5.4bn takeover
By City AM
Peter Hargreaves, who co-founded the investment platform with Stephen Lansdown in 1981, will be stepping down from the board of the company, months after its 拢5.4bn takeover
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Porsche sales plunge in 海角视频 as luxury carmaker grapples with tariffs
By City AM
The luxury car maker sold 19,393 cars in 2025, down from 23,495
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'Mentally it is catastrophic': Tech boss on why firms that scrap diversity schemes will lose out
Black Communities
As the 海角视频 marks Black History Month, a Bristol entrepreneur speaks out about the impact of abandoning DEI schemes
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'London is not the 海角视频': Why Manchester could become the destination of choice for Australian firms
Exports
Mayor and tech leaders join forum on global investment in the city region
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Welsh regions need to come under WRU control says Paul Thorburn
RugbyTalk
The former Welsh captain said that whatever the number of regions taken forward by the WRU they shouldn't consist of any non Welsh qualified players.
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