Welsh shops and hairdressers are expected to get the green light to open on March 15 as guidance is pushed out to retailers ahead of that date.
The next 21 day restrictions review announcement takes place on Friday and comes as cases continue to fall and the number of vaccinations given out increases rapidly.
This has now given the Welsh Government "headroom" to release some of the restrictions on the economy that were introduced on December 20 as infections surged in Wales.
Tourism, leisure, non-essential retail and close contact services have remained shut since that date.
At its worst the infection rate rose to over 650 per 100,000 in Wales but it is now at 51 for the latest seven day rolling period.
This means the scope is now there to move down the Covid Alert Levels in Wales.
It is now widely expected that unless there is any sudden change that non-essential retail and most close contacts services will be able to reopen from Monday March 15.
Friday is also expected to be when Welsh Government confirms if parts of the tourism sector can reopen from the Easter weekend at the start of April.
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CBI Wales has been asked to help distribute from Welsh Government ahead of that date.
Ian Price, CBI Wales Director, said: “With transmission rates heading in the right direction and incredible progress being made on vaccination, non-essential retailers and close contact service providers will be looking to the prospect of a mid-March reopening with huge sense of relief.
“As jobs and livelihoods still hang in the balance, the prospect of bringing some economic activity back to struggling high streets and city centres represents a real step in the right direction for communities and businesses across Wales.
“But this optimism must remain tempered. Wales can’t afford for another sharp rise in transmission rates and for the country to return to a cycle of damaging restrictions.
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"That’s why the Welsh Government’s approach of staggered reopening of sectors has the backing of Wales’s business community.
“As we move closer to proposed reopening dates, firms will be looking to work with government to ensure the process happens as safely and effectively as possible. Early sight of guidance will help significantly to ensure that happens.”