The maker of Guinness is to invest £16m into its packaging facility in Runcorn.
Diageo will use the money to "significantly upgrade" its bottling line and expand warehousing capacity.
The drinks giant added the investment will support the growth of Guinness Draught and Guinness Zero.
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The group also announced a further £24.5m would be spent on more than doubling the canning production at its Belfast base.
The company said: "Diageo is making the investment to meet global demand for Guinness products from domestic and export markets, with the expansion set to support accelerated production and product innovation.
"It will enhance efficiency and competitiveness at both sites. Construction is set to begin immediately with capacity at both facilities expected to come online in 2023."
Aidan Crowe, operations director for beer at Diageo, added: "This expansion is a significant investment in the development of our packaging facilities.
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"The projects in Belfast and Runcorn will support our growth ambitions, helping us to deliver end-to-end product innovation, and reinforce our agility to meet demand and provide excellent service to our customers around the world."
Diageo’s Runcorn packaging plant marked its 50th anniversary in 2020.
There are around 200 employees on the 18-acre site and it operates on a 24/7 basis.