Electric vehicle (EV) production has started at Stellantis's factory in Ellesmere Port, Cheshire.
The company said it is the º£½ÇÊÓÆµâ€™s only dedicated EV manufacturing plant.
Electric vans such as the Vauxhall Combo Electric, Opel Combo Electric, Peugeot e-Partner, Citroen e-Berlingo and Fiat E-Doblo will be made at the site.
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A £100m investment by Stellantis secured the future of the former Vauxhall car manufacturing site, which had been in doubt due to post-Brexit trading arrangements.
The factory is solely producing EVs, with the sale of new petrol and diesel cars and vans being banned in the º£½ÇÊÓÆµ from 2030.
Business Secretary Kemi Badenoch said: "Today's announcement, in which Ellesmere Port becomes the º£½ÇÊÓÆµ's first electric vehicle-only manufacturing plant and the first Stellantis plant globally dedicated to electric vehicles, is a very visible demonstration that this government has got the right plan for the º£½ÇÊÓÆµâ€™s automotive sector.
"Alongside recent investments from other major vehicle manufacturers, we are ensuring the º£½ÇÊÓÆµ remains at the forefront of automotive innovation as well as securing jobs in this critical industry and its wider supply chain."
Stellantis Ellesmere Port plant director Diane Miller added: "The start of electric vehicle production at Ellesmere Port signals a bright future for the plant, ensuring it will continue to manufacture vehicles for many years to come.
"With Vauxhall’s long history of º£½ÇÊÓÆµ manufacturing, it’s especially fitting that the first electric model to roll off Ellesmere Port’s production line is a Combo Electric, whilst the welcome addition of the Fiat E-Doblo to the plant is a positive reflection of increasing electric vehicle demand."